Medullary Thyroid Carcinoma [electronic resource] : Biology – Management – Treatment / edited by Friedhelm Raue.

1st ed. 2015.
Cham : Springer International Publishing : Imprint: Springer, 2015.
Recent results in cancer research 0080-0015 ; 204
Recent results in cancer research
1 online resource.
Human genetics.
Nuclear medicine.
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Mode of Access: World Wide Web.
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This book offers a comprehensive overview of medullary thyroid carcinoma, both in the more common sporadic form and in the familial form, multiple endocrine neoplasia (MEN) types 2A and 2B. The coverage includes, but is not limited to, molecular biology and genetics, pathology, clinical presentation, imaging techniques, surgical treatment, and follow-up. The role of calcitonin as a highly sensitive and specific tumor marker for the screening, diagnosis, and follow-up of MTC and metastatic disease is described, and the significance of other tumor markers is also considered. With regard to treatment, the use of thyroidectomy is fully discussed, including in children carrying the mutations in the RET proto-oncogene considered causative for MEN 2. Additionally, the value of tyrosine kinase inhibitors as the most effective treatment modality in patients with a large tumor burden or rapid tumor growth, or both, is explained. Medullary Thyroid Carcinoma and Multiple Endocrine Neoplasia Type 2 will be an ideal source of up-to-date information for a wide range of practitioners, including endocrinologists, oncologists, internal medicine specialists, geneticists, and nuclear medicine physicians.
Thyroid C-Cell Biology and Oncogenic Transformation
Histopathology of C cells and medullary thyroid carcinoma
Epidemiology and clinical presentation of Medullary Thyroid Carcinoma
Medullary thyroid carcinoma: Imaging
Calcitonin as a Biomarker for Medullary Thyroid Carcinoma
Hereditary Medullary Thyroid Cancer, Genotype phenotype correlation
Pheochromocytomas in Multiple Endocrine Neoplasia 2
Primary hyperparathyroidism in Multiple Endocrine Neoplasia 2 Syndrome
Surgical treatment of  medullary thyroid carcinoma
Long term follow up in medullary thyroid carcinoma
Use of Tyrosine Kinase Inhibitors for Treatment of Medullary Thyroid Carcinoma.
Raue, F. (Friedhelm), editor.
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10.1007/978-3-319-22542-5 doi
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Restricted for use by site license.
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