Franklin

Melanoma Development : Molecular Biology, Genetics and Clinical Application / edited by Anja K. Bosserhoff.

Publication:
Cham : Springer International Publishing : Imprint: Springer, 2017.
Format/Description:
Book
1 online resource
Edition:
2nd ed. 2017.
Contained In:
Springer eBooks
Status/Location:
Loading...

Options
Location Notes Your Loan Policy

Details

Subjects:
Medicine.
Cancer research.
System Details:
text file PDF
Summary:
This book focuses on malignant melanoma, discussing the current state of scientific knowledge and providing insights into the underlying basic mechanisms, the molecular changes, genetics and genomics. Human Melanoma is a dangerous type of skin cancer affecting an increasing population, and a better understanding of its development will help in finding sophisticated targeted therapies. The second revised edition features the latest research findings and offers updates on the latest advances and potential novel melanoma therapies. It is a valuable resource for researchers and clinicians working in the fields of melanoma, cancer research and therapy as well as dermatology.
Contents:
Clinicopathologic Overview of Melanoma
Revisiting Epidermal Melanocytes: Regulation of Their Survival, Proliferation, and Function in Human Skin
Melanoma Epidemiology
Melanoma Genetics and Genomics
Transcriptional Regulation in Melanoma
MiRNAs in Malignant Melanoma
Altered Signal Transduction Pathways in Melanoma
Proteases in Melanoma
Cell-cell contacts in melanoma and the tumor microenvironment
Regulation of Apoptosis in Melanoma Cells: Critical Targets for Therapeutic Strategies
Senescence
Melanoma Stem Cells
The Birth of Malignancy: Embryogenesis and Melanoma
Tumor Microenvironment for Melanoma Cells
Melanoma Model Systems
New Approaches to Signaling
Immune checkpoint inhibitors in melanoma define a new area in immunotherapy aiming for cure. .
Contributor:
Bosserhoff, Anja K. editor.
SpringerLink (Online service)
Other format:
Printed edition:
ISBN:
9783319413198
Publisher Number:
10.1007/978-3-319-41319-8 doi
Access Restriction:
Restricted for use by site license.