Franklin

How tobacco smoke causes disease : the biology and behavioral basis for smoking-attributable disease - a report of the surgeon general. [electronic resource]

Other Title:
How Tobacco Smoke Causes Disease
Publication:
Rockville, MD : U.S. Dept. of Health and Human Services, Public Health Service, Office of the Surgeon General ; Washington, DC : For sale by the Supt. of Docs., U.S. G.P.O., 2010.
Format/Description:
Government document
Book
1 online resource (xv, 704 p ) ill. (some col.) ;
Subjects:
Tobacco use -- Health aspects.
Smoking -- Health aspects.
Tobacco smoke pollution -- Health aspects.
Medical subjects:
Tobacco -- adverse effects.
Disease -- etiology.
Smoking -- adverse effects.
Tobacco Smoke Pollution -- adverse effects.
Tobacco Use Disorder -- complications.
Substance-Related Disorders.
Air Pollution.
Smoke.
Habits.
Solanaceae.
Pathologic Processes.
Particulate Matter.
Behavior.
Mental Disorders.
Angiosperms.
Pathological Conditions, Signs and Symptoms.
Environmental Pollution.
Diseases.
Public Health.
Embryophyta.
Complex Mixtures.
Behavior and Behavior Mechanisms.
Psychiatry and Psychology.
Chemicals and Drugs.
Environment and Public Health.
Streptophyta.
Viridiplantae.
Health Care.
Plants.
Eukaryota.
Organisms.
Tobacco Use Disorder.
Disease.
Smoking.
Tobacco.
Tobacco Smoke Pollution.
Form/Genre:
Electronic books
Language:
English
Summary:
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Contents:
Introduction, evaluation of evidence on mechanisms of disease production, and summary
The changing cigarette
Chemistry and toxicology of cigarette smoke and biomarkers of exposure and harm
Nicotine addiction: past and present
Cancer
Cardiovascular diseases
Pulmonary diseases
Reproductive and developmental efffects
A vision for the future.
Notes:
Shipping list no.: 2011-0184-P.
Includes bibliographical references and index.
Contributor:
United States. Public Health Service. Office of the Surgeon General.
ISBN:
0-16-084078-3
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