Franklin

Gene family targeted molecular design [electronic resource] / edited by Karen E. Lackey.

Other records:
Publication:
Hoboken, N.J. : John Wiley & Sons, c2009.
Format/Description:
Book
1 online resource (382 p.)
Subjects:
Pharmacogenomics.
Drugs -- Design.
Form/Genre:
Electronic books.
Language:
English
Summary:
As research progresses and information continues to proliferate in the field of molecular design for therapeutic use, there is a need for a reference that brings current theory and proven practice together in a how-to volume. This reference guides scientists new to the field on how to design small molecules that interact with critical protein targets. The chapters condense useful material into a manageable format which is carefully organized and presented. It offers an essential resource for a variety of chemists in academia, and the biotech and pharmaceutical industries, as well as profession
Contents:
Drug discoveries by gene family / Karen E. Lackey
G-protein coupled receptors / Stephen L. Garland and Tom D. Heightman
Ion channels gene family : strategies for discovering ion channel drugs / Maria L. Garcia and Gregory J. Kaczorowski
Integrins / David D. Miller
Strategies for discovering kinase drugs / Jerry L. Adams ... [et al.]
Protease-directed drug discovery / Richard Sedrani, Ulrich Hommel, and Jor̈g Eder
Small-molecule inhibitors of protein-protein interactions : challenges and prospects / Adrian Whitty
Transporters / Anne Hersey, Frank E. Blaney, and Sandeep Modi
Nuclear receptor drug discovery / Hiroyuki Kagechika and Aya Tanatani
Summary and comparison of molecules designed to modulate druggable targets in the major gene families / Karen E. Lackey.
Notes:
Description based upon print version of record.
Includes bibliographical references and index.
Contributor:
Lackey, Karen.
ISBN:
1-282-68586-4
9786612685866
0-470-42393-5
0-470-42392-7
OCLC:
437247214
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