Botulinum neurotoxin injection manual / editors, Katharine E. Alter, Nicole A. Wilson.

New York, New York : Demos Medical, 2015.
1 online resource (369 p.)

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Botulinum toxin -- Therapeutic use.
Nervous system -- Diseases -- Treatment.
Electronic books.
The Essential Guide for Clinicians Who Prescribe and Inject BoNTs. This is a detailed and practical guide to botulinum neurotoxin therapy (BoNT) and the wide range of applications for neurological and pain disorders. A unique reference source for new injectors and experienced clinicians alike, this indispensable manual provides information on dose, dilution, and indications for all four FDA-approved toxins in one handy text. Following a brief review of relevant pharmacology, the book provides product information and comparative distinctions between the four FDA-approved toxins (Botox , Myobloc
Cover; Title; Copyright; Contents; Contributors; Preface; Share Botulinum Neurotoxin Injection Manual; Section One: Botulinum Neurotoxin: Basic Science and Reconstitution; Chapter 1: Pharmacology of Botulinum Neurotoxins; Normal Neurotransmitter Release; BoNTs Synthesis and Structure; BoNT Binding/Blocking; BoNT Potency and Dosing; Clinical Implications of BoNT Pharmacology; Antigenicity, Antibody Formation, and Nonresponsiveness to BoNT; Safety; Central Effects of BoNTs; Summary; Chapter 2: Comparison of Botulinum Neurotoxin Products; BoNT Approvals
BoNT Products: Antigenicity, Dilution, and DiffusionBoNT Products: Potency and Dose; Converting Units/Dose Among BoNT Products; Summary; Chapter 3: Neurotoxin Storage, Reconstitution, Handling, and Dilution; Serotype B BoNT; Serotype A BoNTs; OnabotulinumtoxinA (Botox®) Reconstitution and Handling; AbobotulinumtoxinA (Dysport®) Reconstitution and Handling; IncobotulinumtoxinA (Xeomin®) Reconstitution and Handling; RimabotulinumtoxinB (Myobloc® in the United States, NeuroBloc® Outside the United States) Reconstitution and Handling; Injection Supplies; Needle Selection
Chapter 4: Guidance Techniques for Botulinum Neurotoxin InjectionsAnatomic Reference Guides, Surface Anatomy, and Palpation Guidance; EMG Guidance; Electrical Stimulation Guidance; B-Mode Ultrasound; Combinations of Techniques; Other Guidance Techniques for BoNT Injections; Summary; Chapter 5: Phenol Nerve Blocks; Why Consider Phenol Neurolysis?; Phenol Mechanism of Action; Muscle Hypertonia; Pattern of Involvement; Injection Technique and Dosing; Musculocutaneous Nerve; Obturator Nerve; Tibial Motor Nerves; Summary; Section Two: Clinical Applications of Botulinum Neurotoxins
Part I: Botulinum Neurotoxins for the Treatment of Muscle Overactivity Associated with Focal Dystonia Syndromes and Upper Motor Neuron SyndromesCraniofacial Dystonia; Chapter 6: Benign Essential Blepharospasm; Chapter 7: Botulinum Neurotoxin Therapy for Hemifacial Spasm; Chapter 8: Botulinum Neurotoxin Injections for Oromandibular Dystonias; Illustrations for Craniofacial Dystonia; Cervical Dystonia; Chapter 9: Botulinum Neurotoxin Injections for Cervical Dystonia; Illustrations for Cervical Dystonia; Upper Limb, Lower Limb, and Trunk Dystonia
Chapter 10: Botulinum Neurotoxin for the Treatment of Idiopathic Primary Focal Limb DystoniaChapter 11: Botulinum Neurotoxin for Treatment of Muscle Overactivity Associated with Upper Motor Neuron Syndromes; Chapter 12: Botulinum Neurotoxin for the Treatment of Trunk Dystonia/Camptocormia; Chapter 13: Botulinum Neurotoxin Injections for the Treatment of Tremor; Illustrations for Upper Limb, Lower Limb, and Trunk Dystonia; Part II: Botulinum Neurotoxins for Neurosecretory Disorders; Chapter 14: Botulinum Neurotoxin Therapy for Problematic Sialorrhea; Condition
Chapter 15: Botulinum Neurotoxin Therapy for Hyperhidrosis
Description based upon print version of record.
Includes bibliographical references and index.
Description based on print version record.
Alter, Katharine E., editor.
Wilson, Nicole A., editor.