Progress in nucleic acid research and molecular biology. Volume 75 [electronic resource] / edited by Kivie Moldave.

Other Title:
Nucleic acid research and molecular biology
Boston ; Amsterdam : Elsevier/Academic Press, c2003.
Progress in nucleic acid research and molecular biology ; v. 75.
Progress in nucleic acid research and molecular biology ; v. 75
1 online resource (371 p.)
Nucleic acids.
Molecular biology.
Electronic books.
Nucleic acids are the fundamental building blocks of DNA and RNA and are found in virtually every living cell. Molecular biology is a branch of science that studies the physicochemical properties of molecules in a cell, including nucleic acids, proteins, and enzymes. Increased understanding of nucleic acids and their role in molecular biology will further many of the biological sciences including genetics, biochemistry, and cell biology. Progress in Nucleic Acid Research and Molecular Biology is intended to bring to light the most recent advances in these overlapping disciplines with a
Front Cover; Nucleic Acid Research and Molecular Biology; Copyright Page; Contents; Some Articles Planned For Future Volume; Chapter 1. Molecular Regulation, Evolutionary, and Functional Adaptations Associated with C to U Editing of Mammalian ApolipoproteinB mRNA; I. RNA Editing: General Overview of Underlying Biochemical Mechanisms and Evolutionary Development; II. C to U RNA Editing; III. C to U ApoB RNA Editing: cis-Acting Elements; IV. C to U ApoB RNA Editing: trans-Acting Factors; V. Summary; Acknowledgments; References
Chapter 2. Polymorphisms in the Genes Encoding Members of the Tristetraprolin Family of Human Tandem CCCH Zinc Finger ProteinsI. Introduction; II. Materials and Methods; III. Results; IV. Discussion; Acknowledgments; References; Chapter 3. Molecular and Cell Biology of Phosphatidylserine and Phosphatidylethanolamine Metabolism; I. Membrane Phospholipids; II. Pathways for Biosynthesis of Phosphatidylserine and Phosphatidylethanolamine; III. Enzymes of Phosphatidylserine Biosynthesis; IV. Enzymes of Phosphatidylethanolamine Biosynthesis; V. Regulation of PS and PE Biosynthesis
VI. Interorganelle Transport of PS and PEVII. Intramembrane Transport of PS and PE; VIII. Biological Functions of PS and PE; IX. Future Directions; References; Chapter 4. DNA-Protein Interactions during the Initiation and Termination of Plasmid pT181 Rolling-Circle Replication; I. Introduction; II. Origins of Replication of the Plasmids of the pT181 Family; III. Initiator Proteins of the Plasmid pT181 Family; IV. Mechanism of Inactivation of the Plasmid pT181 Family Rep Proteins; V. Role of Host Proteins in pT181 RC Replication; VI. Replication of the Lagging Strand of Plasmid pT181
VII. Conclusions and Future DirectionsAcaknowldgment; References; Chapter 5. Herpes Simplex Virus Type-1: A Model for Genome Transactions; I. Introduction to Herpesviridae; II. HSV-1 Life Cycle, Genome Structure, and Replication Genes; III. Initiation of Replication; IV. Elongation; V. Interaction of the HSV-1 DNA Replication Machinery with DNA Damage; VI. Homologous Recombination; VII. Concluding Remarks; Acknowledgments; References; Chapter 6. Enzymology and Molecular Biology of Glucocorticoid Metabolism in Humans; I. Introduction; II. Glucocorticoid Action; III. The Free Hormone Hypothesis
IV. Glucocorticoid ReceptorsV. Nongenomic Action of Glucocorticoids; VI. Glucocorticoid Resistance; VII. 11 b-Hydroxysteroid Dehydrogenase (11 b-HSD) as Prereceptor Control; VIII. Hydroxysteroid Dehydrogenases: Physiological Role .; IX. The History of Two Isoforms: 11 b-HSD Type 1 and 11 b-HSD Type 2; X. A (Patho)physiological Role for 11 b-HSD 1 and 11 b-HSD 2; XI. 11 -HSD 2 and the Syndrome of ''Apparent Mineralocorticoid Excess'' (AME); XII. 11 b-Hydroxysteroid Dehydrogenase Type 1 (11 b-HSD 1); XIII. Conclusions; References
Chapter 7. Dancing with Complement C4 and the RP-C4-CYP21-TNX (RCCX) Modules of the Major Histocompatibility Complex
Description based upon print version of record.
Moldave, Kivie, 1923-
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