Vitamins and the immune system [electronic resource] / editor-in-chief Gerald Litwack.

Amsterdam ; Boston : Elsevier/AP, 2011.
1 online resource (503 p.)
1st ed.
Vitamins and hormones ; v. 86.
Vitamins and hormones, 0083-6729 ; v. 86

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Immune system.
Electronic books.
First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists and molecular biologists. Others interested in the structure and function of biologica
Front Cover; Vitamins and Hormones: Vitamins and the Immune System; Copyright; Former Editors; Contents; Contributors; Preface; Chapter 1: Vitamin D Regulation of Immune Function; I. Introduction; II. 1,25(OH)2D Production in Cells of the Immune System: Comparisons to Renal Production; III. Role of Vitamin D in the Adaptive Immune Response; IV. Clinical Implications of the Inhibition of the Adaptive Immune Response; V. Role of Vitamin D in the Innate Immune Response; VI. Conclusion; Acknowledgments; References; Chapter 2: Vitamin D and Innate and Adaptive Immunity; I. Introduction
II. Antibacterial Actions of Vitamin DIII. Vitamin D and Antigen Presentation; IV. Vitamin D and Adaptive Immunity; V. Vitamin D, the Immune System and Human Health; VI. Conclusions and Future Directions; References; Chapter 3: Dendritic Cells Modified by Vitamin D: Future Immunotherapy for Autoimmune Diseases; I. Introduction; II. DCs and Their Role in the Immune System; III. Vitamin D Metabolism in DCs; IV. Modulation of DC Function by VDR; V. Application of VD3-Modulated DCs in Treatment of Autoimmune Diseases; VI. Toward Development of Clinically Applicable VD3-DCs; VII. Conclusions
ReferencesChapter 4: Retinoic Acid, Immunity, and Inflammation; I. Introduction; II. Overview of Vitamin A Metabolism and Function; III. RA in Regulation of Myeloid Cell Development; IV. RA and Effector T Cells; V. RA and Regulatory T Cells; VI. RA in Regulation of Antibody Responses; VII. RA and Tissue Inflammation; VIII. Conclusions and Remaining Issues; Acknowledgments; References; Chapter 5: Vitamin A and Retinoic Acid in the Regulation of B-Cell Development and Antibody Production; I. Introduction; II. The Vitamin A-Retinoic Acid Signaling System
III. RA as a Factor in B-Cell Maturation, Activation, and ProliferationIV. Transcription Factors, CSR, and B-Cell Differentiation Toward the PC Phenotype; V. RA as a Factor in Germinal Center Formation; References; Chapter 6: Retinoic Acid Production by Intestinal Dendritic Cells; I. Introduction; II. Backgrounds and General Effects of Vitamin A on Host Defense Systems; III. Regulation of Gut-Specific Homing of Lymphocytes by Dendritic Cells; IV. Imprinting of Gut-Homing Specificity on Lymphocytes by Retinoic Acid
V. Regulation of Functional Differentiation of Lymphocytes by Retinoic Acid-Producing Dendritic CellsVI. Identification of Retinoic Acid-Producing Dendritic Cells; VII. The Origin of Retinoic Acid-Producing Dendritic Cells; VIII. Induction of Retinoic Acid-Producing Capacity in Dendritic Cells; IX. Degradation of Retinoic Acid In Vivo and In Vitro; X. Conclusions and Future Directions; Acknowledgments; References; Chapter 7: Immune Regulator Vitamin A and T Cell Death; I. Introduction; II. Mechanism of Action of Vitamin A; III. Cell Death Pathways; IV. Forms of T Cell Death
V. Regulation of Thymocyte Cell Death by Vitamin A
Description based upon print version of record.
Includes bibliographical references and index.
Litwack, Gerald.