Dopamine / edited by Marco Diana, Gaetano Di Chiara, Pierfranco Spano.
- First edition.
- Amsterdam, Netherlands ; Oxford, [England] : Elsevier, 2014.
- Progress in brain research ; Volume 211.
Progress in Brain Research, 0079-6123 ; Volume 211
1 online resource (320 p.)
- Dopamine -- Receptors.
Dopamine -- Physiological effect.
- Electronic books.
- Progress in Brain Research is a well-established international series examining major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume, concentrates on state-of-the-art of dopamine research: from basic science to clinical applications. It covers topics including thalamostriatal synapses as a substrate for dopamine action; the multilingual nature of dopamine neurons; ethanol-mechanisms along the mesolimbic dopamine system, and much more. Progress in Brain Research is the most acclaimed and accomplished ser
- Front Cover; Dopamine; Copyright; Contributors; Preface; Contents; Chapter 1: Thalamostriatal synapses-another substrate for dopamine action?; 1. The ``Other ́ ́ Striatal Input; 2. Thalamostriatal Targets; 3. Formation and Function of Thalamostriatal Synapses; 4. Impact of Thalamic Changes in Parkinson's Disease on the Motor System; 5. Spine Loss in Striatal Neurons After Dopamine Removal; Acknowledgments; References; Chapter 2: Life-long consequences of juvenile exposure to psychotropic drugs on brain and behavior; 1. Introduction
2. Effects of Juvenile Methylphenidate+Fluoxetine Treatment on Gene Regulation in the Striatum2.1. Effects of Acute and Repeated MPH+FLX Treatment on Striatal IEG Expression; 2.2. Effects of Acute and Repeated MPH+FLX Treatment on Striatal Neuropeptide Expression; 3. Effects of Juvenile Methylphenidate+Fluoxetine Treatment on Molecular Signaling in the Midbrain and Behavior; 3.1. Effects of Juvenile MPH, FLX, and MPH+FLX Exposure on Responses to Aversive Stimuli; 3.2. Effects of Juvenile MPH, FLX, and MPH+FLX Exposure on ERK Signaling in the VTA
3.3. Reversal of Combined MPH+FLX-Induced Behavioral Despair in Adulthood4. Discussion and Conclusions; Acknowledgments; References; Chapter 3: The role of learning-related dopamine signals in addiction vulnerability; 1. Background; 1.1. Overview; 2. Model-free and Model-based Learning from Rewards; 2.1. Model-Based Learning; 2.2. Model-Free Prediction-Error Learning; 3. Phasic Dopamine Signals Represent Model-free Prediction Errors; 3.1. Causal Role of (Dopamine-Mediated) Prediction Errors in Learning; 3.2. Phasic Dopamine Signals in Model-Based Learning
4. Behavioral Characteristics of Model-free and Model-based Choices4.1. Outcome Identity; 4.2. Pavlovian Approach and Consummatory Behaviors; 4.3. Instrumental Behavior; 4.4. Pavlovian-Instrumental Transfer (PIT); 4.5. Motivational Shifts; 4.6. Unlearning; 5. Individual Variability; 5.1. Sign-Tracking and Goal-Tracking; 5.1.1. Behavior; 5.1.2. Dopamine Signals During Acquisition; 5.1.3. Dopamine Signals After Acquisition; 5.2. Incentive Salience Accounts of the Sign-Tracking/Goal-Tracking Variability; 5.2.1. Behavior; 5.2.2. Dopamine
5.3. Reinforcement Learning Accounts of the Sign-Tracking/Goal-Tracking Variability5.3.1. Behavior; 5.3.2. Dopamine Signals During Acquisition; 5.3.3. Dopamine Signals After Acquisition; 5.3.4. Goal-Trackers; 6. Addiction; 6.1. Phasic Dopaminergic Signals in Addiction; 6.2. Individual Variability in Addiction Vulnerability; 6.3. Shifts Toward Model-Free Learning in Addiction; 6.4. Conclusions; Acknowledgments; References; Chapter 4: Dopaminergic function in relation to genes associated with risk for schizophrenia: translational mutant mouse m ...; 1. Introduction
2. Mice Mutant for Dopamine-related Genes
- Description based upon print version of record.
Includes bibliographical references and index at the end of each chapters.
Description based on online resource; title from PDF title page (ebrary, viewed July 9, 2014).
- Diana, Marco, editor.
Di Chiara, Gaetano, editor.
Spano, Pierfranco, editor.
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