Franklin

Principles of evolutionary medicine / Peter Gluckman, Centre for Human Evolution, Adaptation and Disease, Liggins Institute, the University of Auckland, New Zealand, Alan Beedle, Centre for Human Evolution, Adaptation and Disease, Liggins Institute, the University of Auckland, New Zealand, Tatjana Buklijas, Centre for Human Evolution, Adaptation and Disease, Liggins Institute, the University of Auckland, New Zealand, Felicia Low, Centre for Human Evolution, Adaptation and Disease, Liggins Institute, the University of Auckland, New Zealand, Mark Hanson, Institute of Developmental Sciences and NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton, UK.

Author/Creator:
Gluckman, Peter D., author.
Publication:
Oxford, United Kingdom : Oxford University Press, 2016.
Format/Description:
Book
xiv, 378 pages : illustrations ; 25 cm
Edition:
Second edition.
Status/Location:
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Subjects:
Medical anthropology.
Human evolution.
Medical genetics.
Medical subjects:
Anthropology, Medical.
Biological Evolution.
Genetics, Medical.
Contents:
Machine generated contents note: pt. 1 FUNDAMENTALS OF EVOLUTIONARY BIOLOGY
1.Introduction
1.1.What is disease?
1.2.What evolution is: fundamental principles
1.3.Time
1.4.Constraints
1.5.We are not alone
1.6.Culture and gene
culture coevolution
1.7.How evolutionary arguments fit alongside other biological perspectives
1.8.Evolution and medicine
Key points
2.Evolutionary theory
2.1.Introduction
2.2.What does evolutionary theory explain?
2.3.How does evolution work?
2.4.Areas of debate and the limitations of the adaptationist argument
2.5.Conclusion
Key points
3.The molecular basis of variation and inheritance
3.1.Introduction
3.2.Genes and disease
3.3.The molecular basis of human genetic variation
3.4.Factors affecting genetic variation
3.5.Single-gene or Mendelian disorders
3.6.No single genes for common diseases
3.7.Epigenetic mechanisms as a cause of variation
3.8.Non-genetic inheritance
Note continued: 3.9.Conclusion
Key points
4.Evolution and development
4.1.Introduction
4.2.Development: pre-ordained or plastic?
4.3.Is development important to evolution?
4.4.Developmental plasticity
4.5.Responses to environmental cues during development
4.6.Epigenetic processes and development
4.7.Learning and instinct
4.8.The evolution of novelty
4.9.Conclusion
Key points
5.The human life history
5.1.Introduction
5.2.General overview of life-history theory
5.3.Body size and shape
5.4.Growth in humans
5.5.Evolutionary analysis of the distinct features of human growth
5.6.Conclusion
Key points
6.Human evolution and the origins of human diversity
6.1.Introduction
6.2.The hominoid clade
6.3.Hominin evolution
6.4.Genomic changes that make us human
6.5.Human adaptation to local selection pressures
6.6.Are humans still evolving?
6.7.Social and medical implications of human diversity
Note continued: 6.8.Conclusion
Key points
pt. 2 EVOLUTION IN HEALTH AND DISEASE
7.An evolutionary framework for understanding human health and disease
7.1.Introduction
7.2.Fundamental principles of evolutionary medicine
7.3.Why has evolution left our bodies vulnerable to disease?
7.4.An evolutionary classification of ultimate mechanisms affecting disease risk
7.5.Testing hypotheses in evolutionary medicine
Key points
8.Reproduction
8.1.Introduction
8.2.Sexual reproduction
8.3.Why did sex evolve?
8.4.Sex determination
8.5.Reproductive strategies
8.6.Mate choice
8.7.Sexual differences in the human
8.8.Sex differences in morbidity and mortality
8.9.Human reproductive life cycle
8.10.Conclusion
Key points
9.Nutritional and metabolic adaptation
9.1.Introduction
9.2.Strategies for energy storage
9.3.Human diet: an evolutionary history
9.4.How can change in the environment increase disease risk?
Note continued: 9.5.Conclusion
Key points
10.Coevolution, infection, and immunity
10.1.Introduction
10.2.Coevolution
10.3.Humans and their associated species
10.4.The challenge of infectious disease
10.5.Pathogen emergence
10.6.Pathogen virulence and transmission
10.7.Host defenses
10.8.Public health measures
10.9.Vaccination
10.10.Antibiotics
10.11.Conclusion
Key points
11.Psychology and behavior
11.1.Introduction
11.2.Biological determinants of culture and behavior
11.3.Evolution of the human brain and behavior
11.4.Evolution of social behavior
11.5.Evolutionary perspectives on psychology
11.6.Evolutionary psychiatry
11.7.Conclusion
Key points
12.Cancer
12.1.Introduction
12.2.Epidemiology of cancer
12.3.Ecology of cancer
12.4.The biology of cancer
12.5.Cancer in the light of evolutionary mechanisms
Note continued: 12.6.Implications of an evolutionary approach for the prevention and treatment of cancer
12.7.Conclusion
Key points
13.Evolutionary principles applied to medical practice and public health
13.1.Introduction: Understanding health and disease from an evolutionary perspective
13.2.Testing evolutionary hypotheses in medicine
13.3.Clinical examples
13.4.An evolutionarily mismatched or novel environment
13.5.Life-history-associated factors
13.6.Excessive and uncontrolled defense mechanisms
13.7.Consequences of coevolution with microbes
13.8.Results of evolutionary constraints
13.9.An apparently harmful allele is maintained by balancing selection
13.10.The consequences of sexual selection
13.11.The outcomes of cladal and demographic history
13.12.Value and limits of an evolutionary medicine perspective
Key points
14.Evolution, medicine, and society
14.1.Introduction
14.2.Origins of Darwin's theory
Note continued: 14.3.From Darwin to "Social Darwinism"
14.4.Eugenics
14.5.The "Modern Synthesis," human evolution, and medicine
14.6.Evolution, society, and religion
14.7.Evolutionary thought and the human condition
Key points.
Notes:
Includes bibliographical references and index.
Local notes:
Acquired for the Penn Libraries with assistance from the George Clapp Vaillant Book Fund.
Contributor:
Beedle, Alan, author.
Buklijas, Tatjana, author.
Low, Felicia, author.
Hanson, Mark A.
George Clapp Vaillant Book Fund.
ISBN:
9780199663927
0199663920
9780199663934
0199663939
OCLC:
946705440