Franklin

Mechanisms Underlying Host-Microbiome Interactions in Pathophysiology of Human Diseases / edited by Jun Sun, Pradeep K. Dudeja.

Publication:
Boston, MA : Springer US : Imprint: Springer, 2018.
Format/Description:
Book
1 online resource (XVIII, 381 pages) : 34 illustrations, 26 illustrations in color.
Series:
Physiology in health and disease
Physiology in Health and Disease
Contained In:
Springer eBooks
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Details

Subjects:
Medicine.
Human physiology.
Medical microbiology.
Internal medicine.
Local subjects:
Biomedicine. (search)
Human Physiology. (search)
Medical Microbiology. (search)
Internal Medicine. (search)
System Details:
text file PDF
Summary:
Only recently have we begun to appreciate the role of microbiome in health and disease. Environmental factors and change of life style including diet significantly shape human microbiome that in turn appears to modify gut barrier function affecting nutrient and electrolyte absorption and inflammation. Approaches that can reverse the gut dysbiosis represent as reasonable and novel strategies for restoring the balance between host and microbes. In the book, we offer summary and discussion on the advances in understanding of pathophysiological mechanisms of microbial host interactions in human diseases. We will not only discuss intestinal bacterial community, but also viruses, fungi and oral microbiome. Microbiome studies will facilitate diagnosis, functional studies, drug development and personalized medicine. Thus, this book will further highlight the microbiome in the context of health and disease, focusing on mechanistic concepts that underlie the complex relationships between host and microbes.
Contents:
Impact of microbes on the intestinal development of the preterm infant
Microbiome: Allergic Diseases of Childhood
Pathogenesis, immunity and the role of microbiome/probiotics in enteric virus infections in humans and animal models
Enteric bacterial regulation of the Wnt/β-catenin signaling
Mechanism underlying beneficial role of probiotics in diarrheal diseases: host-microbe interactions
The influence of microbiota on gastrointestinal motility
Altered microbiota and their metabolism in host metabolic diseases
The influence of the microbiota on the etiology of colorectal cancer
Oral microbiome: Potential link to systemic disease and cancer
Candida albicans commensalism and human diseases
Fecal microbiota transplants: current knowledge and future directions
Statistical Models and Analysis of Microbiome Data from mice and human.
Contributor:
Sun, Jun. editor.
Dudeja, Pradeep K. editor.
SpringerLink (Online service)
Other format:
Printed edition:
ISBN:
9781493975341
Publisher Number:
10.1007/978-1-4939-7534-1 doi
Access Restriction:
Restricted for use by site license.