Franklin

Influenza Virus [electronic resource] : Methods and Protocols / edited by Yoshihiro Kawaoka, Gabriele Neumann.

Publication:
Totowa, NJ : Humana Press, 2012.
Series:
Methods in Molecular Biology, Methods and Protocols, 1064-3745 ; 865
Springer Protocols (Springer-12345)
Methods in Molecular Biology, Methods and Protocols, 1064-3745 ; 865
Format/Description:
Book
1 online resource (X, 234 pages) : 34 illustrations, 5 illustrations in color.
Subjects:
Medicine.
Virology.
Infectious diseases.
Local subjects:
Medicine & Public Health.
Infectious Diseases.
Virology.
System Details:
text file PDF
Summary:
Reports of influenza-like illnesses date back to the Middle Ages, and outbreaks of influenza likely afflicted humans long before that. Over the last half century, influenza virus research has led to the development of two classes of antivirals - ion channel and neuraminidase inhibitors. Recently, a method of the artificial generation of an influenza virus was established. This system has been instrumental in the development of novel influenza vaccines and in the understanding of viral pathogenicity and the functions of viral proteins. Influenza Virus: Methods and Protocols summarizes the current techniques that have made this progress possible, ranging from protocols for virus isolation, growth, and subtyping to procedures for the efficient generation of any influenza virus. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.   Authoritative and easily accessible, Influenza Virus: Methods and Protocols seeks to serve both professionals and novices with the techniques used in numerous laboratories around the world that are, thus, the building blocks that underpin almost all influenza virus research.
Contents:
Influenza Viruses - An Introduction
Influenza Virus Isolation
Influenza Virus Titration, Antigenic Characterization, and Serological Methods for Antibody Detection
Diagnosis of Influenza Virus
Solid-phase Assays of Receptor-binding Specificity
The Chemiluminescent Neuraminidase Inhibition Assay: A Functional Method for Detection of Influenza Virus Resistance to the Neuraminidase Inhibitors
The Fluorescence Neuraminidase Inhibition Assay: A Functional Method for Detection of Influenza Virus Resistance to the Neuraminidase Inhibitors
Animal Models
Influenza Virus Surveillance, Vaccine Strain Selection and Manufacture
Genetic Engineering of Live Attenuated Influenza Viruses
Influenza A Virus Molecular Virology Techniques
Reverse Genetics of Influenza Viruses
Genetic Analysis.
Contributor:
Kawaoka, Yoshihiro, 1955- editor.
Neumann, Gabriele. editor.
SpringerLink (Online service)
Contained In:
Springer eBooks
Other format:
Printed edition:
ISBN:
9781617796210
Publisher Number:
10.1007/978-1-61779-621-0 doi
Access Restriction:
Restricted for use by site license.
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