Franklin

Neuroprotection Methods and Protocols [electronic resource] / edited by Tiziana Borsello.

Publication:
Totowa, NJ : Humana Press, 2007.
Format/Description:
Book
1 online resource (XII, 239 pages) : 48 illustrations, 3 illustrations in color.
Series:
Methods in molecular biology 1064-3745 ; 399
Springer Protocols (Springer-12345)
Methods in Molecular Biology, 1064-3745 ; 399
Contained In:
Springer eBooks
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Subjects:
Medicine.
Neurosciences.
Neurology.
Cytology.
Local subjects:
Biomedicine. (search)
Neurosciences. (search)
Neurology. (search)
Cell Biology. (search)
System Details:
text file PDF
Summary:
Due to an aging population, the incidence of age-related neurodegenerative diseases is expected to rise dramatically. In Neuroprotection Methods and Protocols, a team of skilled, renowned researchers provide step-by-step laboratory protocols intended to slow or prevent the progression of such diseases. Focusing on neuroprotective approaches, this volume describes basic scientific discoveries and the application of such research within different laboratories in a clear and systematic way in order to orient scientists in this complicated field. The chapters follow the Methods in Molecular Biology™ series format, consisting of readily reproducible methods, lists of the necessary materials, and a Notes section which aids the researcher in solving and avoiding technical problems. Comprehensive and easy to use, Neuroprotection Methods and Protocols is the perfect reference for basic neuroscientists hoping to move forward the ever-important field of neuroprotection and neuronal death research. .
Contents:
Neuronal Death and Neuroprotection: A Review
The Use of Propidium Iodide to Assess Excitotoxic Neuronal Death in Primary Mixed Cortical Cultures
A Modified Silver Technique (de Olmos Stain) for Assessment of Neuronal and Axonal Degeneration
Model of Acute Injury to Study Neuroprotection
Organotypic Entorhino-Hippocampal Slice Cultures-A Tool to Study the Molecular and Cellular Regulation of Axonal Regeneration and Collateral Sprouting In Vitro
Role of Nrf2-Dependent ARE-Driven Antioxidant Pathway in Neuroprotection
Biochemical Methods to Assess the Coupling of Brain Energy Metabolism in Control and Disease States
A Method for Isolating Prosurvival Targets of NF-?B/Rel Transcription Factors
Functional Cloning of Genes Regulating Apoptosis in Neuronal Cells
Characterization of mRNA Expression in Single Neurons
Brain on a Chip: A Method to Detect Novel Neuroprotective Candidate Targets
Intracerebral Infusion of Neurotrophic Factors
Synthesis of Cell-Penetrating Peptides and Their Application in Neurobiology
The Stem Cells as a Potential Treatment for Neurodegeneration
In Vivo Tomographic Imaging Studies of Neurodegeneration and Neuroprotection: A Review.
Contributor:
Borsello, Tiziana. editor.
SpringerLink (Online service)
Other format:
Printed edition:
ISBN:
9781597455046
Publisher Number:
10.1007/978-1-59745-504-6 doi
Access Restriction:
Restricted for use by site license.