Franklin

Biomarkers in Liver Disease [electronic resource] / edited by Vinood B. Patel, Victor R. Preedy.

Publication:
Dordrecht : Springer Netherlands : Imprint: Springer, 2019.
Series:
Biomedical and Life Sciences (Springer-11642)
Biomarkers in Disease: Methods, Discoveries and Applications, 2542-3657
Biomarkers in Disease: Methods, Discoveries and Applications, 2542-3657
Format/Description:
Book
1 online resource (800 pages) : 50 illustrations
Subjects:
Oncology.
Oncology  .
Toxicology.
Local subjects:
Cancer Research.
Oncology.
Pharmacology/Toxicology.
System Details:
text file PDF
Summary:
In the past decade there has been a major sea change in the way disease is diagnosed and investigated due to the advent of high throughput technologies, such as microarrays, lab on a chip, proteomics, genomics, lipomics, metabolomics et cetera These advances have enabled the discovery of new and novel markers of disease relating to autoimmune disorders, cancers, endocrine diseases, genetic disorders, sensory damage, intestinal diseases et cetera In many instances these developments have gone hand in hand with the discovery of biomarkers elucidated via traditional or conventional methods, such as histopathology or clinical biochemistry. Together with microprocessor-based data analysis, advanced statistics and bioinformatics these markers have been used to identify individuals with active disease or pathology as well as those who are refractory or have distinguishing pathologies. New analytical methods that have been used to identify markers of disease and is suggested that there may be as many as 40 different platforms. Unfortunately techniques and methods have not been readily transferable to other disease states and sometimes diagnosis still relies on single analytes rather than a cohort of markers. There is thus a demand for a comprehensive and focused evidenced-based text and scientific literature that addresses these issues. Hence the formulation of Biomarkers in Disease The series covers a wide number of areas including for example, nutrition, cancer, endocrinology, cardiology, addictions, immunology, birth defects, genetics, and so on. The chapters are written by national or international experts and specialists.
Contents:
Liver biomarkers and their applications to nutritional interventions in animal studies
AST-to-platelet ratio index (APRI) as marker in liver disease.-Inflammatory biomarkers in ascites
Biomarkers for hepatocellular carcinoma in East Asia
Liver disease and acylcarnitines as mechanistic biomarkers.-Type VI Collagen: Biological Functions and its Neo-epitope as Hepatic Fibrosis Biomarker
Fibrinogen α-chain as a serum marker of liver disease
Monocyte chemotactic protein-1 (cytokine, receptors,and gene polymorphisms) in hepatitis
Biomarkers for Recurrence of Hepatocellular Carcinoma.-Graft-derived cell-free DNA as a biomarker in liver transplantation
Serum sialic acid as a biomarker in liver disease
CD133 and EpCAM as Biomarkers in Liver Diseases
Traditional markers in liver disease
Biomarkers of extracellular matrix remodeling in liver diseases
Squamous Cell Carcinoma Antigen- Immunoglobulin M (SCCA-IgM) as biomarker in liver disease: biological aspects and clinical applications
microRNA-155 and microRNA-196b in hepatitis C virus infection
Immunological biomarkers in liver transplantation
Phosphatidylethanol and alcohol use in liver disease patients
Interaction of sialyltransferases, sialidases and sialic acids in liver diseases and applications to biomarker discovery
Biomarkers to monitor graft function following liver transplantation
YKL-40 as a biomarker of liver diseases
Peripheral venous, portal venous, hepatic venous, arterial and intrahepatic cytokine levels as biomarkers and functional correlations
Histological Biomarkers of Non-Alcoholic Fatty Liver Disease
Vascular cell adhesion molecule-1 (vcam-1) expression in liver disease
Bilirubin as a biomarker in liver disease
Hydroxyproline as a biomarker in liver disease
Genetic biomarkers of paracetamol-induced acute liver failure
PNPLA3 polymorphism and Nonalcoholic Fatty Liver Disease
Hepascore and it's application to liver disease
Model for End-Stage Liver Disease (MELD) Score as a Biomarker
Biomarkers in focus: Alanine Aminotransferase
PTX3 as a biomarker of liver disease.
Contributor:
Patel, Vinood B. editor., Editor,
Preedy, Victor R. editor., Editor,
SpringerLink (Online service)
Contained In:
Springer Nature Living Reference
ISBN:
978-94-007-7742-2
9789400777422
Publisher Number:
10.1007/978-94-007-7742-2 doi
Access Restriction:
Restricted for use by site license.
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