Neuroscience in the 21st Century / edited by Donald W. Pfaff, Nora D. Volkow.

New York, NY : Springer New York : Imprint: Springer, 2019.
Biomedical and Life Sciences (Springer-11642)
1 online resource (XL, 3112 pages)
Local subjects:
Neurosciences. (search)
Neurobiology. (search)
Neurology. (search)
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Edited and authored by a wealth of international experts in neuroscience and related disciplines, the aim behind this key new resource is to offer medical students and graduate researchers around the world a comprehensive introduction and overview of modern neuroscience.  Neuroscience research is certain to prove a vital element in combating mental illness in its various incarnations, a strategic battleground in the future of medicine,  as the prevalence of mental disorders is becoming better understood each year. Hundreds of millions of people worldwide are affected by mental, behavioral, neurological and substance use disorders. The World Health Organization estimated in 2002 that 154 million people globally suffer from depression and 25 million people from schizophrenia; 91 million people are affected by alcohol use disorders and 15 million by drug use disorders. A more recent WHO report shows that 50 million people suffer from epilepsy and 24 million from Alzheimer's and other dementias. Because neuroscience takes the etiology of disease-the complex interplay between biological, psychological, and sociocultural factors-as its object of inquiry, it is increasingly valuable in understanding an array of medical conditions. A recent report by the United States' Surgeon General cites several such diseases: schizophrenia, bipolar disorder, early-onset depression, autism, attention deficit/ hyperactivity disorder, anorexia nervosa, and panic disorder, among many others. Not only is this volume a boon to those wishing to understand the future of neuroscience, it also aims to encourage the initiation of neuroscience programs in developing countries, featuring as it does an appendix full of advice on how to develop such programs.  With broad coverage of both basic science and clinical issues, comprising 106 chapters from a diversity of international authors and including complementary video components, Neuroscience in the 21st Century will serve as a comprehensive resource to students and researchers alike.
Section 1 Basic Neuroscience
Part 1 Biophysics
1Water, ions, membranes, pumps and transporters
2 Voltage-gated ion channels.- 3 Ionotropic glutamate receptors
4 Signal transduction-dependent channels
5 Membrane Potentials
Part 2 Development
6 Stem cells: Neural stem cells in cerebral cortex development
7Adult neurogenesis
8 Dendrites: a key structural element of neurons
Part 3 Cell Biology of neurons and glia
9 Dendritic function
10 Axonal transport
11 Cell biology of the synapse
12 Molecular regulation of synaptic release
13 The postsynaptic density
14 Gap junctions, electric synapses
15 Glial cells
16 Immune system cells
17 Psychoneuroimmune phenomena: Neuroimmune interactions
Part 4 Sensory Systems (Neuroanatomy and Physiology)
18 Retina: Neuroanatomy and physiology
19 The superior colliculus and visual thalamus
20 Cortical processing of visual signals
21 Audition: Hearing and Deafness
22 Somatosensation: end organs for tactile sensation
3 Taste
24 Olfaction
25 Visuomotor Integration
26 Vestibular inputs: The Vestibular System
27 Kinesthetic inputs
28 PainPart 5
Motor Control
29 Spinal motoneurons
30 Spinal interneurons
31 Systems descending from the brainstem: Basic principles
32 Systems descending from the brainstem: Functional recovery following damage
33 Basal ganglia: Basic principles
34 Dystonia
35 Cerebellum - Anatomy and Function
36 The Cerebellum: Eye Movements
37 Cortical motor control
38 Locomotion: Circuits and Physiology
39 PosturePart 6
Neurophysiology of  Other, Specific CNS Regions and Networks
40Basic principles of mammalian CNS systems
41Frontal cortex
42 Limbic cortex: The functional neuroanatomy of emotion and hedonic processing
43 Hypothalamus
44 Autonomic nervous systems
46 Spinal reflexes Part 7
Neurochemistry, Neuropharmacology
47 Transmitters and peptides: Basic principles
48 Transmitter and peptide receptors: Basic principles
49 Opioid peptides
50 Trophic factors: Neurotrophic factors
51 Brain Energy Metabolism
52 Blood Brain Barrier
Part 8 Neuroendocrinology
53 Brain control over pituitary gland hormones
54 Hormone effects on behavior
55 Critical periods during development: Hormonal influences on neurobehavioral transitions across the lifespan
56 Mechanisms of homeostatically regulated behaviors
57 Mechanisms of behaviors related to reproduction
58 Seasonal rhythms in behavior
Part 9 Regulation of Natural Behaviors
59 Circadian physiology
60 The suprachiasmatic nucleus and the circadian timekeeping system of the body
61 Sleep regulation and insomnia
62 Genomic imprinting and brain function
63 Epigenetic mechanisms: DNA methylation and histone protein modification
64 Stress research: past, present and future
65 Fear
66 Aggression
67 Emotions studied by imaging of the human brain: The somatic and emotional motor systems
68 Parental behavior
69 Sexual behavior
70 Social behavior
Part 10
Cognitive Neuroscience
71 Elementary CNS arousal
72 Neurobiology of Learning and Memory
73 Cognitive Functions as Revealed by Imaging of the Human Brain
74 Aging of the brain
Part 11 Computational Neuroscience
75 Computational neuroscience of synapses and neurons
76 Computational neuroscience of neuronal networks
77 Biological Modeling
Section 2 Clinical Neuroscience
Part 12 Developmental Disorders
78 Prader-Willi and Angelman Syndromes
79 Fragile X-Associated Disorders
80 Fetal alcohol syndrome
81 Autism
82 Anorexia nervosa and bulimia
Part 13 Systems Disorders
83 Sleep disorders
Traumatic brain damage
85 Spinal cord damage
86 Ischemic Stroke - Basic pathophysiology and clinical implication
Part 14 Pain
87 Non-migrainous headache
88 Migraine
89 Central mechanisms of pain suppression
Part 15 Neuroimmune Disorders
90 Multiple sclerosis
91 Myasthenia gravis
Infections of the nervous system
Part 16 Addictive Disorders
93 Psychostimulants and addiction
94 Neurobiology of Alcohol Addiction
95 Internet addiction
96 Abuse of performance enhancing drugs
97 Food addiction. - Part 17 Degenerative Diseases
98 Motor neuron disease: Amyotrophic lateral sclerosis
99 Parkinson's disease
100 Huntington's disease. - 101 Problems during aging (Alzheimer's, and others).
Part 18 Gender Identity
102 Sexual differentiation of the human brain in relation to gender-identity, sexual orientation and neuropsychiatric disorders
Part 19
Psychiatric Disorders
103 Depressive disorders
104 The Neurobiology of Bipolar Disorder
105 Schizophrenia BM Appendix Seven Steps to Setting up a Neuroscience Program in a Developing Country
Pfaff, Donald W. editor., Editor,
Volkow, Nora D. editor., Editor,
SpringerLink (Online service)
Contained In:
Springer Nature Living Reference
Publisher Number:
10.1007/978-1-4614-6434-1 doi
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Restricted for use by site license.
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