Oxford textbook of cancer biology / edited by Francesco Pezzella, Mahvash Tavassoli, David J. Kerr.

Other Title:
Cancer biology
First edition.
Oxford : Oxford University Press, 2019.
Oxford textbooks in oncology
xvi, 483 pages : illustrations (chiefly color) ; 28 cm.
Cancer -- Molecular aspects.
Cancer cells.
Cancer cells.
Cancer -- Molecular aspects.
Medical subjects:
Neoplasms -- genetics.
The Oxford Textbook of Cancer Biology brings together the multifaceted branches of the study of cancer biology into one coherent volume, providing a comprehensive and up-to-date account of this complex and rapidly evolving field.
SECTION I The multicellular organism; 1. The multicellular organism and cancer; 2. DNA repair and genome integrity; 3. Evolution and cancer; SECTION II The aetiology of cancer; 4. Genetics and genetic instability in cancer; 5. Epigenetics; 6. Viral carcinogenesis-an overview; 7. Chemical carcinogens; 8. Radiation as a carcinogen; SECTION III How the cancer cell works; 9. Growth factors and associated signalling pathways in tumour progression and in cancer treatment; 10. Hormones and cancer; 11. Oncogenesis and tumour suppression; 12. The signalling pathways in cancer; 13. Cell cycle control; 14. Cancer and cell death; 15. Telomerase and immortalization; 16. Cancer metabolism; 17. Chaperones and protein quality control in the neoplastic process; 18. Oxygen and cancer: The response to hypoxia; 19. Invasion, metastasis, and tumour dormancy; 20. Cancer stem cells; SECTION IV Cancer microenvironment; 21. Cancer-​associated stroma; 22. Blood vessels and cancer; 23. Cancer immunology; SECTION V Global vision of cancer; 24. Molecular profiling in cancer research and personalized medicine; 25. Proteomics and metabolomics applications in cancer biology; 26. Cancer systems biology: From molecular profiles to pathways, signalling networks, and therapeutic vulnerabilities; 27. Cancer biology through immunohistology; SECTION VI The biology of cancer treatment; 28. Principles of chemotherapy; 29. Immunotherapy and tumour resistance to immune-​mediated control and elimination; 30. Biological effect of radiotherapy on cancer cells; SECTION VII Conclusions; 31. Benign tumours: The forgotten neoplasms; 32. Conclusions: Cancer biology, a moveable feast; Index.
Includes bibliographical references and index.
Pezzella, Francesco, editor.
Tavassoli, Mahvash, editor.
Kerr, David J., editor.
Other format:
Electronic version: Oxford textbook of cancer biology.
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