Franklin

Structural Immunology / edited by Tengchuan Jin, Qian Yin.

Publication:
Singapore : Springer Singapore : Imprint: Springer, 2019.
Format/Description:
Book
1 online resource (XIII, 226 pages) : 86 illustrations, 84 illustrations in color.
Edition:
1st ed. 2019.
Series:
Biomedical and Life Sciences (Springer-11642)
Advances in experimental medicine and biology 0065-2598 ; 1172
Advances in Experimental Medicine and Biology, 0065-2598 ; 1172
Contained In:
Springer eBooks
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Details

Subjects:
Immunology.
Proteins.
Molecular biology.
Local subjects:
Immunology. (search)
Protein Structure. (search)
Molecular Medicine. (search)
Receptors. (search)
System Details:
text file PDF
Summary:
This book presents a comprehensive overview of important immune molecules and their structure-function relationships. The immune system is highly complex, consisting of a network of molecules, cells, tissues and organs, and the immune reaction is involved in various physiological as well as pathological processes, including development, self-tolerance, infection, immunity, and cancer. Numerous molecules participate in immune recognition, inhibition and activation, and these important immune molecules can be roughly divided into cell surface receptors, intracellular receptors and intracellular signaling molecules. The study of how these immune molecules function at molecular level has laid the foundation for understanding the immune system. The book provides researchers and students with the latest research advances concerning the structural biology of key immune molecules/pathways, and offers immunologists essential insights into how these immune molecules function.
Contents:
Structural basis for signalling through shared common g chain cytokines
MHC Molecules, T Cell Receptors, Natural Killer Cell Receptors, and Viral Immunoevasins-Key Elements of Adaptive and Innate Immunity
Structures of Immune Checkpoints: An Overview on the CD28-B7 Family
Interleukin-10 family cytokines immunobiology and structure
Structural insights into the interleukin-17 family cytokines and their receptors
Structural biology of NOD-like receptors
AIM2 Inflammasome Assembly and Signaling
Structures of RIG-I-like receptors and insights into viral RNA sensing
Structural Insight of Gasdermin Family Driving Pyroptotic Cell Death
NF-κB, IκB, and IKK: Integral Components of Immune System Signaling.
Contributor:
Jin, Tengchuan, editor., Editor,
Yin, Qian, editor., Editor,
SpringerLink (Online service)
Other format:
Printed edition:
Printed edition:
Printed edition:
ISBN:
978-981-13-9367-9
9789811393679
Publisher Number:
10.1007/978-981-13-9367-9 doi
Access Restriction:
Restricted for use by site license.