Franklin

Studies on Arthritis and Joint Disorders / edited by Maria Jose Alcaraz, Oreste Gualillo, Olga Sánchez-Pernaute.

Publication:
New York, NY : Springer New York : Imprint: Humana, 2013.
Format/Description:
Book
1 online resource (XII, 411 pages) : 41 illustrations, 15 illustrations in color.
Edition:
1st ed. 2013.
Series:
Biomedical and Life Sciences (Springer-11642)
Oxidative stress in applied basic research and clinical practice 2197-7224
Oxidative Stress in Applied Basic Research and Clinical Practice, 2197-7224
Contained In:
Springer eBooks
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Subjects:
Oxidative stress.
Cytology.
Rheumatology.
Local subjects:
Oxidative Stress. (search)
Cell Biology. (search)
Rheumatology. (search)
System Details:
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Summary:
Joint diseases are a major public health concern. Reactive oxygen species are mediators in pathways associated with joint tissue injury. Oxidative Stress in Applied Basic Research and Clinical Practice: Studies on Arthritis and Joint Disorders provides background to understanding the role of reactive oxygen species in joint diseases, as well as therapeutic strategies for their regulation. International experts discuss recent advances on experimental and clinical data focused on free radical-mediated mechanisms of disease. The book also addresses the protective role of antioxidants against the insult of reactive oxygen species in rheumatic diseases.
Contents:
Biomarkers of oxidative stress in joint diseases
Regulation of T-cell functions by oxidative stress
Nitric oxide and the respiratory chain in synovial cells and chondrocytes
Adipokines, molecular players at the crossroad between inflammation and oxidative stress. Role in arthropathies
Regulation of cartilage and bone metabolism by oxidative stress
Role of oxidative stress in bone aging
Genetic Component of Oxidative Stress in Rheumatoid Arthritis
Oxidative stress in rheumatoid arthritis
Oxidative stress and premature atherosclerosis in RA
Role of Oxidative Stress and Reactive Oxygen Radicals in the Pathogenesis of Systemic Sclerosis
Antioxidant and anti-inflammatory properties of heme oxygenase-1 in osteoarthritic articular cells
Oxidative stress at the crossroads between osteoarthritis and metabolic syndrome
Metabolic syndrome and gout
Natural Antioxidants in the pharmacological treatment of rheumatic immune and inflammatory diseases
Antioxidants in the treatment of osteoarthritis and bone mineral loss
Anti-cytokine agents to combat oxidative stress
Oxidative Conditioning and treatment for Osteoarthritis
The role of sirtuins in arthritis
MicroRNA molecules, master regulators, biomarkers and potential therapies
Estrogen-dependent transcriptional activity, a protection against ROS in osteoarthritis.
Contributor:
Alcaraz, María José, editor., Editor,
Gualillo, Oreste, editor., Editor,
Sanchez-Pernaute, Olga, editor., Editor,
SpringerLink (Online service)
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Printed edition:
Printed edition:
Printed edition:
ISBN:
978-1-4614-6166-1
9781461461661
Publisher Number:
10.1007/978-1-4614-6166-1 doi
Access Restriction:
Restricted for use by site license.