Franklin

Mechanisms of DNA repair by recombination / James E. Haber.

Author/Creator:
Haber, James E. , author
Publication:
London : Henry Stewart Talks, 2009.
Format/Description:
Video
1 online resource (1 streaming video file (66 min.)) : color, sound.
Series:
Henry Stewart talks. Biomedical & life sciences collection. Introduction to human genetics : fundamentals and latest advances.
Introduction to human genetics : fundamentals and latest advances, 2056-452X
Status/Location:
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Details

Subjects:
Human genetics.
Medical genetics.
Medical subjects:
DNA Repair.
Genetics, Medical.
System Details:
Mode of access: World Wide Web.
Contents:
Contents: Genome instability in tumor cells
Mutations
Loss of heterozygozity
Repair of chromosome breaks
Double-strand break repair is essential for life
Replication stalling and fragile sites
Programmed DSBs
Repair of DSBs arising during DNA replication by recombination
The homologous recombination machinery
E. coli
Holliday junctions
Break-induce replication
Single strand annealing
Types of homologous recombination
Observing DNA repair in real time
Molecular studies of recombination
Nonhomologous end-joining (NHEJ) pathways
Copy number variation
Gene amplification.
Notes:
Animated audio-visual presentation with synchronized narration.
Title from title frames.
Publisher Number:
2555 Henry Stewart Talks
Access Restriction:
Restricted for use by site license.