Franklin

The endoplasmic reticulum as a most efficient antibody factory / Roberto Sitia.

Author/Creator:
Sitia, Roberto. , author
Publication:
London : Henry Stewart Talks, 2007.
Format/Description:
Video
1 online resource (1 streaming video file (47 min.)) : color, sound.
Series:
Henry Stewart talks. Biomedical & life sciences collection. Endoplasmic reticulum : fundamentals and role in disease.
The endoplasmic reticulum : fundamentals and role in disease, 2056-452X
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Details

Medical subjects:
Endoplasmic Reticulum.
System Details:
Mode of access: World Wide Web.
Contents:
Contents: Studies on the synthesis, assembly and secretion of antibodies during B cell development reveal fundamental properties of the endoplasmic reticulum as a protein factory
How do cells regulate the formation, isomerisation and reduction of disulfide bonds?
How do plasma cells manage to secrete massive amounts of antibodies?
Is antibody production somehow controling plasma cell lifespan?
Answers to these questions have profound implications in biotechnology and medicine, as they may help design better bioreactors for the production of recombinant proteins and better therapies for multiple myeloma and other secretory tumors.
Notes:
Animated audio-visual presentation with synchronized narration.
Title from title frames.
Publisher Number:
1556 Henry Stewart Talks
Access Restriction:
Restricted for use by site license.