Chromosome bi-orientation in yeast / Michael J. R. Stark.

Author/Creator:

Stark, Michael J. R. , author

Publication:

London : Henry Stewart Talks, 2009.

Series:

Henry Stewart talks. Biomedical & life sciences collection. Cell division cycle : controlling when and where cells divide and differentiate.
The cell division cycle : controlling when and where cells divide and differentiate, 2056-452X

Format/Description:

Video
1 online resource (1 streaming video file (54 min.)) : color, sound.

Medical subjects:

Cell Cycle.
Genes, cdc.

System Details:

Mode of access: World Wide Web.

Contents:

Contents: What is chromosome biorientation and why is it important?
Failure to bi-orient a chromosome will lead to mis-segregation/aneuploidy
Modes of sister chromatid attachment to spindle microtubules
The budding yeast (Saccharomyces cerevisiae) as a model for studying chromosome bi-orientation
Monitoring sister centromeres on individual yeast chromosomes
Kinetochore capture
Achieving chromosome bi-orientation: mechanisms
Geometry-dependent mechanism or a correction mechanism?
Yeast Ipl1p kinase
Chromosomes fail to bi-orient with high frequency in Ipl1 mutants
How might Ipl1p kinase promote bi-orientation?
Yeast chromosomes can bi-orient without the need for back-to-back geometry
How does Ipl1p kinase promote bi-orientation?
The yeast chromosomal passenger complex
Models for tension-sensing
What are the targets of Ipl1p kinase at the kinetochore?
Model for Ipl1 / Aurora function in promoting bi-orientation.

Notes:

Animated audio-visual presentation with synchronized narration.
Title from title frames.

Publisher Number:

2259 Henry Stewart Talks

Access Restriction:

Restricted for use by site license.

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