Biomolecular Feedback Systems / Richard M. Murray, Domitilla Del Vecchio.
- Course Book
- Princeton, NJ : Princeton University Press, 
1 online resource : 13 halftones. 113 line illustrations 3 tables
- Biological control systems.
- In English.
- System Details:
- Mode of access: Internet via World Wide Web.
text file PDF
- This book provides an accessible introduction to the principles and tools for modeling, analyzing, and synthesizing biomolecular systems. It begins with modeling tools such as reaction-rate equations, reduced-order models, stochastic models, and specific models of important core processes. It then describes in detail the control and dynamical systems tools used to analyze these models. These include tools for analyzing stability of equilibria, limit cycles, robustness, and parameter uncertainty. Modeling and analysis techniques are then applied to design examples from both natural systems and synthetic biomolecular circuits. In addition, this comprehensive book addresses the problem of modular composition of synthetic circuits, the tools for analyzing the extent of modularity, and the design techniques for ensuring modular behavior. It also looks at design trade-offs, focusing on perturbations due to noise and competition for shared cellular resources.Featuring numerous exercises and illustrations throughout, Biomolecular Feedback Systems is the ideal textbook for advanced undergraduates and graduate students. For researchers, it can also serve as a self-contained reference on the feedback control techniques that can be applied to biomolecular systems.Provides a user-friendly introduction to essential concepts, tools, and applicationsCovers the most commonly used modeling methodsAddresses the modular design problem for biomolecular systemsUses design examples from both natural systems and synthetic circuitsSolutions manual (available only to professors at press.princeton.edu)An online illustration package is available to professors at press.princeton.edu
Chapter 1. Introductory Concepts
Chapter 2. Dynamic Modeling of Core Processes
Chapter 3. Analysis of Dynamic Behavior
Chapter 4. Stochastic Modeling and Analysis
Chapter 5. Biological Circuit Components
Chapter 6. Interconnecting Components
Chapter 7. Design Tradeoffs
- Description based on online resource; title from PDF title page (publisher's Web site, viewed 23. Mai 2019)
- Murray, Richard M., author.
- Contained In:
- De Gruyter University Press Library.
- Publisher Number:
- 10.1515/9781400850501 doi
- Access Restriction:
- Restricted for use by site license.
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