Franklin

Cell Engineering and Regeneration / edited by Jeffrey M. Gimble, Darja Marolt, Richard Oreffo, Heinz Redl, Susanne Wolbank.

Publication:
Cham : Springer International Publishing : Imprint: Springer, 2020.
Format/Description:
Book
1 online resource (20 illustrations)
Series:
Engineering (Springer-11647)
Tissue Engineering and Regeneration
Tissue Engineering and Regeneration
Contained In:
Springer Nature Living Reference
Status/Location:
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Details

Subjects:
Biomedical engineering.
Biomedical materials.
Regenerative medicine.
Tissue engineering.
Biophysics.
Local subjects:
Biomedical Engineering and Bioengineering. (search)
Biomaterials. (search)
Regenerative Medicine/Tissue Engineering. (search)
Biological and Medical Physics, Biophysics. (search)
System Details:
text file PDF
Summary:
This reference work presents the origins of cells for tissue engineering and regeneration, including primary cells, tissue-specific stem cells, pluripotent stem cells and trans-differentiated or reprogrammed cells. There is particular emphasis on current understanding of tissue regeneration based on embryology and evolution studies, including mechanisms of amphibian regeneration. The book covers the use of autologous versus allogeneic cell sources, as well as various procedures used for cell isolation and cell pre-conditioning , such as cell sorting, biochemical and biophysical pre-conditioning, transfection and aggregation. It also presents cell modulation using growth factors, molecular factors, epigenetic approaches, changes in biophysical environment, cellular co-culture and other elements of the cellular microenvironment. The pathways of cell delivery are discussed with respect to specific clinical situations, including delivery of ex vivo manipulated cells via local and systemic routes, as well as activation and migration of endogenous reservoirs of reparative cells. The volume concludes with an in-depth discussion of the tracking of cells in vivo and their various regenerative activities inside the body, including differentiation, new tissue formation and actions on other cells by direct cell-to-cell communication and by secretion of biomolecules.
Contents:
Cells for Cartilage Regeneration
Primary Cells: Periosteal Cells
Stem Cells: Bone Marrow Derived - MSC and HSC
Embryonic Stem Cells
Induced Pluripotent Stem Cells and Transdifferentiation
Stem Cells - Aging Aspects
Biophysical Preconditioning and Modulation - Low Level Light Therapy (LLLT) in Wound Healing"
Biophysical Preconditioning and Modulation
miRNA Modulation
Cell Storage - Activity Control
Challenges and Status of Adipose Cell Therapies: Translation and Commercialization
Peripheral Blood Mononuclear Cell Secretome for Tissue Repair
Systemic Applications
Cell Culture Conditions - Cultivation of Stem Cells under Dynamic Conditions
Mesenchymal Stem Cell Secretome for Tissue Repair
Cell Culture Conditions - Cell Derived Factors
Cell Differentiation
Primary Cells - overview of Different Cell Types Contributing to Muscle Repair and Regeneration
Stem Cells: Umbilical Cord/Wharton's Jelly Derived
Use of Xenogeneic Cells
Material Based Preconditioning and Modulation (Molecules, Patterns and Surface Hardness)
Cell Aggregates - Sheets
Epigenetic Modulation Approaches
Cell Tracking
Stem Cells: Olfactory Mucosa
Basics of Self-Regeneration
Translating from Animal Systems (Models) to Human Cells
Basics of Amphibian Self-Regeneration
Biological Augmentation for Tendon Repair - Lessons to be Learned from Development, Disease, and Tendon Stem Cell Research
Primary Cells: Liver Cells
Stem Cells: Amniotic Fluid
Adipose Derived Stem Cells
Stem Cells: Perivascular Origin
Cell Sorting
Immortalized Primary Cells for Test Systems
Cell Transfection
Molecular Crowding - (in Cell Culture)
Primary Cells: Pancreatic Cells
Primary Cells: Schwann Cells and Neurons
Human Amniotic Membrane Cells: Basic Characteristics
Stem Cells: Skin
Blood Derived Stem Cells
Use of Autologous or Allogeneic Cells
Cell Tools for Mechanistic Studies
Primary Cells: Keratinocytes and Skin Fibroblasts
Pluripotent Stem Cells from Different Sources
Muse Cells
Biochemical Preconditioning and Modulation
Cell Sheets
Two Level Approaches
Cell-Cell Communication by Exosomes and Microvesicles
Local Applications
Endogenous Cell Catching
Cell-Cell Contact
Activation and Differentiation of Endogenous Stem Cells During a Wound Healing
Needs for Clinical Application of Stem Cells
Regulatory Aspects of Cell Therapy.-.
Contributor:
Gimble, Jeffrey M. editor., Editor,
Marolt, Darja. editor., Editor,
Oreffo, Richard. editor., Editor,
Redl, Heinz, editor., Editor,
Wolbank, Susanne. editor., Editor,
SpringerLink (Online service)
ISBN:
978-3-319-37076-7
9783319370767
Publisher Number:
10.1007/978-3-319-37076-7 doi
Access Restriction:
Restricted for use by site license.