Franklin

Bone Adaptation : In Silico Approach / by Yoshitaka Kameo, Ken-ichi Tsubota, Taiji Adachi.

Author/Creator:
Kameo, Yoshitaka author., Author,
Edition:
1st ed. 2018.
Publication:
Tokyo : Springer Japan : Imprint: Springer, 2018.
Series:
Engineering (Springer-11647)
Frontiers of biomechanics 2199-8515 ; 2
Frontiers of Biomechanics, 2199-8515 ; 2
Format/Description:
Book
1 online resource (XIV, 209 pages) : 93 illustrations, 24 illustrations in color.
Subjects:
Biomedical engineering.
Orthopedics.
Biomathematics.
Biophysics.
Regenerative medicine.
Tissue engineering.
Computer simulation.
Local subjects:
Biomedical Engineering and Bioengineering. (search)
Orthopedics. (search)
Physiological, Cellular and Medical Topics. (search)
Biological and Medical Physics, Biophysics. (search)
Regenerative Medicine/Tissue Engineering. (search)
Simulation and Modeling. (search)
System Details:
text file PDF
Summary:
This book focuses on the systems biomechanics of bone remodeling that provide a multiscale platform for bone adaptation, spanning the cellular, tissue, and organ levels. The mathematical model explained in each section provides concrete examples of in silico approaches for bone adaptation. It will be immensely useful for readers interested in bone morphology and metabolism and will serve as an effective bridge connecting mechanics, cellular and molecular biology, and medical sciences. These in silico approaches towards exploring the mechanisms by which the functioning of dynamic living systems is established and maintained have potential for facilitating the efforts of graduate students and young researchers pioneering new frontiers of biomechanics.
Contents:
Overview: In Silico Approaches to Understand Bone Adaptation
Microscopic Fluid Flow Analysis in an Osteocyte Canaliculus
Macroscopic Fluid Flow Analysis in a Poroelastic Trabecula
Estimation of Bone Permeability for Poroelastic Analysis
Modeling Trabecular Bone Adaptation Induced by Flow Stimuli to Osteocytes
Effects of Local Bending Load on Trabecular Bone Adaptation
Cancellous Bone Adaptation Predicted by Remodeling Simulations
Trabecular Surface Remodeling toward Uniform Local Stress State
Spatial and Temporal Regulation of Cancellous Bone Structure by Trabecular Surface Remodeling
Comparison of Mechanical Quantities as Bone Remodeling Stimuli
Trabecular Surface Remodeling Simulation of Cancellous Bone Using Image-Based Voxel Finite Element Models
Functional Adaptation of Cancellous Bone in Human Proximal Femur
3D Trabecular Remodeling in Human Proximal Femur: Approach to Understanding Wolff's Law
Trabecular Structural Changes in a Vertebral Body with a Fixation Screw.
Contributor:
Tsubota, Ken-ichi, author., Author,
Adachi, Taiji, author., Author,
SpringerLink (Online service)
Contained In:
Springer eBooks
Other format:
Printed edition:
Printed edition:
Printed edition:
ISBN:
978-4-431-56514-7
9784431565147
Publisher Number:
10.1007/978-4-431-56514-7 doi
Access Restriction:
Restricted for use by site license.
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