This volume first presents evidence for the earthworm's immune system; the results strongly suggest that certain molecules of the earthworm's immune system may be exploited as natural antibiotics - thus the biomedical applications.
Intro Preface Contents Introduction to the Earthworm Immune System The Earthworm: A New Model with Biomedical Applications Coelomocytes (Leukocytes) Cytochemical Properties of Earthworm Coelomocytes Enriched by Percoll Earthworm Coelomocytes: Convenient Model for Basic and Applied Sciences Use of Fluorescent Probes to Analyze the Killing, Encapsulation and Chemotaxis Functions of Coelomocytes of the Earthworm, Lumbricus terrestris Comparative Analysis of Earthworm Immune System Using Cell Surface and Intracellular Markers Antimicrobial Activity and Cytotoxicity Coelomic Fluid from Lumbricus terrestris and Eisenia foetida inhibits Escherichia coli Earthworm Humoral Immune System: Interaction of Hemolysins with Lipid Membranes Requires Sphingolipids Evidence for a Perforin-like Cell-mediated Cytolysis by Earthworm Coelomocytes The Evolution of Cell Killing: When a Target Cell Became "Invited" to Choose How to Die Other Annelid Models: Leeches Leech Immune Responses: Contributions and Biomedical Applications New Powerful Cascade Coagulant Inhibitors Isolated from the Gut of the Leech: Theromyzon Tessulatum Other Invertebrate Models The Ancient Principle of Membrane Permeabilization: Structure and Function of Evolutionarily Divergent Cytolytic and Antimicrobial Polypeptides From Earthworm to Mussel Innate Immunity The Prophenoloxidase Activating System in Invertebrates: A Short Review Mitogenic, Lectin and Cytokine-like Activities Mitogenic Factors in Eisenia Foetida Coelomic Fluid as Regulatory Molecules TNF Analogue in Earthworms and the Role of Lectin-Saccharide Interactions in Regulatory Function of Primitive Cytokines The Functional Relevance of the Lectin-like Activities of Cytokines: TNF as an Illustrative Example Activities against Parasites. Invertebrate Immune Responses to Eukaryotic Parasites: Reaction of Coelomocytes of Lumbricus Terrestris to Native and Non-native Parasite Summary and Perspectives An Overview of Cytolytic Factors in Eisenia Foetida Coelomic Fluid Bibliography of Edwin L. Cooper emphasizing on earthworms (1966-2002) Author Index B C D E F G H K L M N P R S T V W.
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Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2021. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.