Essentials of blood product management in anesthesia practice / Corey S. Scher, Alan David Kaye, Henry Liu, Seth Perelman, Sarah Leavitt, editors.
- Cham : Springer, 
1 online resource
Blood -- Transfusion.
Blood -- Transfusion -- Complications.
- Electronic books.
- This comprehensive book is written to inform and improve outcomes of patients in need of blood management during surgical procedures. Information is presented in an accessible format, allowing for immediate use in clinical practice. Beginning with an overview of the history of blood transfusions, early chapters present the foundational information needed to comprehend information in later chapters. Nuanced procedures, drugs, and techniques are covered, including new biologicals to assist clotting and blood substitutes. Further discussions focus on potential complications seen in blood transfusions, such as diseases of the coagulation system, pathogen transmissions, and acute lung injuries. Chapters also examine the complexities of treating specific demographics, of which include the geriatric patient and patients suffering from substance abuse. Essentials of Blood Product Management in Anesthesia Practice is an invaluable guide for anesthesiologists, surgeons, trauma physicians, and solid organ transplant providers.
1: The History of Blood Transfusion and Blood Management
The Legacy of Hippocrates
Antiquity and the Concept of Transfusion
The Discovery of the Circulation
The Cellular Elements of Blood
The Royal Society Transfusion Experiments
James Blundell and Obstetricians Revive Transfusion Medicine
The Legacy of Karl Landsteiner
The Search for an Anticoagulant
Fractionated Blood Products
Blood Management in the Modern Era
The Future of Blood Management
2: Modern Blood Banking
The ABO and Rh Blood System
Other Blood Antigen Systems
The Human Leukocyte Antigen System
Serologic Versus Computer Crossmatch
Creutzfeldt-Jakob Disease (CJD)
Pathogen Reduction Technology (PRT)
3: Blood Component Therapy
Fresh Frozen Plasma
4: The Coagulation System and Blood Clot Stability
Coagulation Factors and Their Functions
Normal Coagulation Cascade
Regulation of Coagulation
Mechanisms of Clot Stability and Fibrinolysis
Factors Affecting Clot Stability
Fibrinolysis: Regulation and Its Role in Disease Process
5: Fibrinolysis, Antifibrinolytic Agents, and Perioperative Considerations
Fibrinolysis and Molecular Regulation
Tranexamic Acid and the Risk of Seizures
Trauma, the Role of Fibrinolysis, and Traumatic Brain Injury
Liver Surgery and Transplantation
Topical Tranexamic Acid
6: Hypercoagulation and Thrombotic Disorders
Primary (Congenital) Hypercoagulable States
Protein C and S Deficiency
Factor V Leiden (Activated Protein C Resistance)
Other Primary Hypercoagulable States
Secondary (Acquired) Hypercoagulable States
Oral Contraceptives and Hormone Replacement Therapy
Other Secondary Hypercoagulable States
7: Diseases or Conditions of Platelet Disorders
Types of Disorders
Thrombocythemia and Thrombocytosis
Inherited Platelet Disorders
Recombinant Activated Factor VII (rFVIIa)
- Includes index.
Online resource; title from PDF title page (SpringerLink, viewed April 12, 2021).
- Scher, Corey S., editor.
Kaye, Alan David, editor.
Liu, Henry, editor.
Perelman, Seth, editor.
Leavitt, Sarah, editor.
- Publisher Number:
- 10.1007/978-3-030-59295-0 doi
- Access Restriction:
- Restricted for use by site license.
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