Franklin

Early detection and treatment of head & neck cancers : theoretical background and newly emerging research / Rami El Assal, Dyani Gaudilliere, Stephen Thaddeus Connelly, editors.

Publication:
Cham, Switzerland : Springer, 2021.
Format/Description:
Book
1 online resource
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Other Title:
Theoretical background and newly emerging research
Subjects:
Head -- Cancer.
Neck -- Cancer.
Form/Genre:
Electronic books.
Electronic books.
Summary:
Head and neck cancer (HNC) is a heterogeneous group of cancers that, if combined, represent one of the most common cancer types. Patients with HNC suffer significant morbidity and mortality due to the importance of the structures involved. Over two-thirds of these patients are diagnosed at a late stage, leading to a poor prognosis. Therefore, advancements in early detection and treatment of HNC are crucial. This second volume provides an up-to-date overview of the theoretical background in the field of head and neck cancer (HNC) as well as of the emerging research that is impacting our understanding of this disease. The book begins with a comprehensive review of the epidemiology, etiology, symptoms, diagnosis, and staging of HNC. Next, it covers the essentials of potentially malignant disorders of the oral cavity, an important variety of HNC. Subsequently, it covers the newly emerging research in the field of HNC. The overall goal is to shift towards precision medicine (discussed in detail in Volume I), which will bring individualized clinical benefit to patients with HNC. This second volume of Early Detection and Treatment of Head & Neck Cancers concludes with the topic of chronic pain associated with HNC, including both the mechanisms of pain and the management strategies, and the emerging oral mucoadhesive drug delivery approach for HNC. All HNC surgeons, scientists, residents, and individuals whose lives have been touched by this disease, will recognize the impact pain has upon a patients health and his or her recovery trajectory.
Contents:
Epidemiology of Head and Neck Cancers
Epidemiology of Head and Neck Premalignant Lesions
Mutational Landscape of Head and Neck Cancers
Genomic and Proteomic Factors of Head and Neck Cancer Progression
Understanding the Role of Exosomes in Molecular Pathogenesis of Cancers including Head and Neck Cancers
Risk of Head and Neck Cancers in Systemic Inflammatory Disorders and after Immunosuppressive Treatment
Metastasis of Brain Tumors (including Glioblastoma) to Head and Neck Region
Virus-associated Head and Neck Cancers in Immunocompromised and Healthy Patients
Orofacial Pain-/Oral Adverse Event-associated with Head and Neck Cancers
EGFR Activation Signature and Modulation in Head and Neck Cancers
Identification of Genetic Differences between Normal and Tumor Tissues in Head and Neck Cancers
Cellular Immune Mechanisms of Natural Killer (NK) Cell, Dendritic Cells (DC) and T Lymphocyte Activation Against Head and Neck Cancers
Statistical Power Analysis in Head and Neck Cancer Studies
Bioethics in Head and Neck Cancer Research
Future Perspective of Head and Neck Cancer Research.
Notes:
Includes index.
Online resource; title from PDF title page (SpringerLink, viewed May 17, 2021).
Contributor:
El Assal, Rami, editor.
Gaudilliere, Dyani, editor.
Connelly, S. Thaddeus, editor.
ISBN:
9783030698522
3030698521
3030698513
9783030698515
OCLC:
1250347523
Publisher Number:
10.1007/978-3-030-69852-2 doi
Access Restriction:
Restricted for use by site license.